A Review: Aedes-Borne Arboviral Infections, Controls and Wolbachia-Based Strategies

Arthropod-borne viruses (Arboviruses) continue to generate significant health and economic burdens for people living in endemic regions. Of these viruses, some of the most important (e.g., dengue, Zika, chikungunya, yellow fever virus), are transmitted mainly by Aedes mosquitoes. Over years, viral infection control has targeted vector population reduction inhibition arboviral replication transmission. This includes methods which classified into chemical, environmental, biological methods. Some may be largely experimental (both field laboratory investigations) or widely practised. Perceptively, one control, particular, Wolbachia-based shows a promising strategy eradicating Aedes-borne arboviruses. can either through artificial introduction Wolbachia, naturally present bacterium that impedes growth mosquitoes heterologous aegypti mosquito vectors (vectors not natural hosts Wolbachia) thereby limiting transmission via albopictus mosquitoes, harbour Wolbachia infection. These strategies potentially undermined tendency lose unfavourable weather conditions high temperature) inhibitory competitive dynamics among co-circulating strains. The main objective this review was critically appraise published articles on specifically highlight use suppress disrupt We retrieved studies transmissions arthropod discussed diseases identify literature gaps will instrumental developing models estimate impact and, essence, different strains features.